In 1999 and 2000, Tiësto collaborated with Ferry Corsten to create Gouryella. His 2000 remix of Delerium’s “Silence” featuring Sarah McLachlan exposed him to more mainstream audiences. In 2001, he released his first solo album, In My Memory. The title track is a remix of an original song written by and featuring Nicola Hitchcock. This album gave him several major hits that launched his career. He was voted World No. 1 DJ by DJ Magazine in its annual Top 100 DJs readership poll consecutively for three years from 2002–04. Just after releasing his second studio album Just Be he performed live at the 2004 Summer Olympics opening ceremony in Athens, the first DJ to play live on stage at an Olympics. In April 2007 Tiësto launched his radio show Tiësto’s Club Life on Radio 538 in the Netherlands and released his third studio album Elements of Life. The album reached number one on the Belgian album chart as well on “Billboard Top Electronic Albums” in the U.S. and received a nomination for a Grammy Award in 2008.Tiësto released his fourth studio album Kaleidoscope in October 2009, followed by “A Town Called Paradise” in 2014. He won the Grammy Award for Best Remixed Recording, Non-Classical for his remixed version of John Legend’s hit “All Of Me” at the 57th Annual Grammy Awards.
Tiesto從學校派對中開始了他的职業打碟生涯，及後在1985年及1993年於荷蘭的几个俱樂部中成為駐場DJ. 在這些年間，他用了Da Joker及DJ Limited這2個別名製作了很多的Hardcore/Gabber音樂. 當時，他在周末晚上10時至早上4時的時候，在一間位於Breda名叫”The Spock”的小俱樂部中的一間分隔開的房中，開始尋找著他的音樂風格. 在1990年的中期，他開始製作著Trance, 及在1997年時與Arny Bink合作開了Black Hole Recordings以推出他的作品. Black Hole Recordings及它的屬下唱片公司Magik Muzik同時簽了Cor Fijneman, Ton TB, 及Mark Norman這幾位Tiësto’s眼中的Trance製作精英及DJs. 他的暢銷單曲包括“Flight 643,” “Lethal Industry,” “Suburban Train,” “Traffic,” 和他重新編曲詮釋的古典作品-巴伯Samuel Barber的弦樂慢板“Adagio for Strings.” Flight 643 曾被[ID&T]票選為電音史上第二最具影響力的舞曲作品,Lethal Industry 則有出神(Trance)樂中最令人難忘的高潮樂段, Traffic 則是他最出名，最具有能量爆發力的一首單曲，並成為荷蘭23年來唯一獲得排行第一的樂曲。